Kvom wrote:
"The tangent angle between the two points becomes a simple calculation."
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Kvom, I'm not "preaching to the choir". I KNOW you know this, but some prior posters might not have been aware of how easy it is to do.
Indeed, it's easy!
Mnemonic for Americans: "Indian Chief Soh Cah Toa". Once you've learned it, you never forget it!
Sin=opposite/hypotenuse, Cosine=adjacent/hypotenuse, Tangent=opposite/adjacent
You might have to come up with your own Mnemonic for other countries/languages.

Simply calculate the one that's most-convenient for the point-pair; The tangent would seem to be the easiest and most-logical one.
Once you've determined the angle of the point-to-point line, calculate the perpendicular for the actual milling tangent angle by just adding or subtracting 90 degrees.
Lloyd