I've been trying a couple different clamping methods and in addition to PinchBlox (
http://www.pinchblox.com/ ) I thought I'd try making a cam lock. I made this one based on the Golden Ratio info found at Wikipedia (
http://en.wikipedia.org/wiki/Golden_ratio ).
Its maximum holding distance is approximately 2" (51mm) and its minimum is about .84" (21mm). When clamping, I use two cams per side, pointing in opposite directions. I tap on one a bit, then tap on the other a bit, alternating until the piece is sufficiently secure. I do it this way to prevent the piece from walking around and if they're facing the right way, the one you're not tapping on, will get tighter as the piece shifts a little. If you have them pointing the wrong way it'll be obvious right away, because the one you're not tapping on will keep getting loose, so just flip them over.
The pattern here is the one I use for .25" (6mm) MDF, but of course it can be adjusted to whatever thickness of scrap you have lying around. I took a guess as to where the center hole should be, and it's not quite perfect but in the end, it works fine in my dusty shop. If you have suggestions for this little fella, let me know.
This is probably basic stuff for folks here, but perhaps it could be useful to someone looking for a cheap clamping method for a CNC router. Thanks for looking.
-Brian